Enterprise is a city in the southeastern part of Coffee County and the southwestern part of Dale County in Southeastern Alabama, United …Enterprise is a city in the southeastern part of Coffee County and the southwestern part of Dale County in Southeastern Alabama, United States. Its population was 28,711 at the 2020 census. Enterprise is the primary city of the Enterprise micropolitan statistical area. It was originally a part of Enterprise–Ozark micropolitan area before being split; for a longer while it was originally part of the Dothan-Enterprise-Ozark combined statistical area but is now its own separate primary statistical area in later censuses.