Persistent hyponatremia despite treatment prompts further evaluation, revealing isolated aldosterone deficiency despite normal adrenal function and leading to effective therapy.

Adults whose blood pressure stays dangerously high despite taking three or more medications now have a new option. The FDA ...

A steroid hormone called aldosterone is linked to an increased risk of kidney failure in patients with chronic kidney disease (CKD), according to a study published in the European Heart Journal today ...

Electrodes were pulled in one stage from thin-wall borosilicate filament capillaries (GC100TF-10, outer diameter 1.0 mm, Clark Electromed, Reading, UK) using a vertical puller. The electrodes had a ...

A drug that has been used to slow progression of kidney and cardiovascular disease in people with type 2 diabetes may also help people with chronic kidney disease who do not have diabetes, according ...

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Lorundrostat, a novel therapy which blocks the production of aldosterone from the adrenal glands, demonstrated clinically meaningful and sustained reductions in blood pressure in 1,083 patients with ...

Findings from a cross-sectional study published in Annals of Internal Medicine implicate the hormone aldosterone as a common and unrecognized contributor to hypertension. Hypertension affects more ...

A team of medical researchers and doctors affiliated with multiple institutions in the U.S. has found, via clinical trial, that the aldosterone synthase inhibitor lorundrostat is likely safe to use ...

When women are hypertensive their physicians should consider measuring their level of aldosterone, a hormone that at high levels damages the cardiovascular system, scientists say. When women are ...

Please provide your email address to receive an email when new articles are posted on . Once-daily lorundrostat safely lowered 24-hour systolic BP compared with placebo in a phase 2 trial. A ...