Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutation of the NOTCH3 gene and is considered a model of 'pure' vascular dementia. MRI ...

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Future Neurology. 2008;3(6):683-704. In a recent meta-analysis, CADASIL patients were reported to also suffer from neuromuscular symptoms, weakness, wasting, reduced/exaggerated tendon reflexes, ...

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited cerebrovascular disease characterized by brain infarcts, cognitive decline and ...