Scientists have been unable to determine the structure of a biologically important so-called GAG proteoglycan -- or even to agree whether these remarkably complex molecules have well-defined ...

Carbohydrates are ubiquitous. They densely carpet cell surfaces. They are the main component of the extracellular matrix that surrounds cells. They are involved in many aspects of cell-cell ...

Despite mass spectrometry's success in the identification and characterization of small molecules (Milestone 7), its application to carbohydrates was initially stymied. This was due to their low vapor ...

Carbohydrates play a wide range of important roles in the body and, despite the challenges posed by glycobiology, are now tempting targets for drug developers. Although several genomes have been ...

Nobody would argue with the statement that proteins are a challenge for computer modelers. Descriptions of their swirls of helices and ribbons, to say nothing of their further folding, can tax even ...

The Max Planck Institute of Colloids and Interfaces (MPICI) has created a carbohydrate sequence that can fold into a stable secondary structure. To date, self-folding biopolymers had only been ...

We need carbohydrates for energy. This energy is essential for our cells to do the work they need to make our organs and systems function.