Obstructive hypertrophic cardiomyopathy (oHCM) is a progressive condition that can worsen over time. So at some point, you might need to make adjustments to your treatment plan to keep your symptoms ...

Trametinib, a mitogen-activated protein kinase (MEK) inhibitor, reduces mortality and morbidity in children with severe hypertrophic cardiomyopathy (HCM) caused by pathogenic variants in the RAS/MAPK ...

Advanced, or end-stage, heart failure is the last stage of cardiomyopathy. Under the American Heart Association and American College of Cardiology classification, it's called Stage D heart failure ...

Medications are the backbone of cardiomyopathy treatment to help you feel better and live longer. Your healthcare team will work with you to optimize your regimen; you play a key role by sticking with ...

Vutrisiran is the first RNAi therapy approved to reduce cardiovascular events in ATTR-CM patients, marking a significant advancement in treatment options. The HELIOS-B trial showed a 28% reduction in ...

Treating children with cardiomyopathy should be personalized based on the root cause, symptoms and progression of the condition in each child , according to a new American Heart Association scientific ...

Study substantially exceeded enrollment target of 500 patientsTopline results anticipated in Q1 2027THE WOODLANDS, Texas, July 27, 2026 (GLOBE ...

Despite noting the high unmet need in Duchenne muscular dystrophy, the FDA panel concluded that trial data lacked substantial evidence of the therapy's effectiveness.

A diagnosis of stress-induced cardiomyopathy is also known as takotsubo cardiomyopathy and broken heart syndrome. It means the heart has been weakened by an acute period of emotional or physical ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNA interference (RNAi) therapeutics company, today announced that the Committee for Medicinal Products for ...

Cardiomyopathy weakens, enlarges, or stiffens the heart muscle. Heart failure is when the heart is unable to pump enough blood around the body, resulting in symptoms. Cardiomyopathy is one of the ...

Hypertrophic cardiomyopathy (HCM) is a genetic condition that can affect the structure and function of the heart. However, people with HCM can typically expect to live a relatively typical life. HCM ...