Most cell signals are chemical in nature. For example, prokaryotic organisms have sensors that detect nutrients and help them ...

Poly(I:C), a synthetic double-stranded RNA, durably suppressed NF1-associated optic pathway glioma growth in mice by engaging ...

Researchers have demonstrated that signals in the intestine produce oscillations that inform cell differentiation.

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

Scientists have discovered a new nerve cell signaling mechanism could transform our understanding of pain and lead to safer, more effective treatments. The study, co-led by Matthew Dalva, a chair in ...

The design of new calcium channels, built bottom-up from scratch, was reported last week in Nature. "Biochemists have been studying ion channels for decades and debating about how they work for almost ...

A study conducted at the Hubrecht Institute reveals that the intestines use the rhythm of a signal to decide which cells to make. Researchers from the Sonnen group discovered that chemical signals ...

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns. Scientists at St. Jude Children's ...

A new study reports that the cytokine IL-17A drives malignant T-cell proliferation in cutaneous T-cell lymphoma by increasing ...