To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send ...

To function normally, nearly every cell in the human body relies on G-protein-coupled receptors (GPCRs) to receive and send ...

ICC is a malignant tumor of the liver characterized by high tumor heterogeneity and poor prognosis. However, there is still a limited understanding of the cellular diversity and molecular basis of ...

The Hippo pathway plays an important role in cell proliferation, differentiation, and cancer occurrence. Yes-associated protein 1 (YAP) is a key effector molecule of Hippo pathway. Previous studies ...

One finding of the study, now published in the Journal of Biological Chemistry, surprised the researchers: The mice were simultaneously protected against hypertension by activating a different ...

FGF21 is primarily known as a metabolic hormone. A new study by researchers at Helmholtz Munich and Ludwig Maximilians ...

Blocking a signaling pathway in certain white blood cells may prevent clots from obstructing blood flow and causing CTEPH, per a new study.

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract, with KIT mutations ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

Cancer cells are remarkably good at adapting to stress. When treatments damage them, they often find new ways to survive, ...