A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.

Because viruses have to hijack someone else’s cell to replicate, they’ve gotten very good at it—inventing all sorts of tricks. A new study from two University of Chicago scientists has revealed how ...

Though treatments are available, there is no cure or vaccine from HIV, which impacts about 38 million people worldwide. It's difficult to target the RNA genome of the HIV virus in part because it ...

HIV, or human immunodeficiency virus, is the retrovirus that leads to acquired immunodeficiency syndrome or AIDS. Globally, about 35 million people are living with HIV, which constantly adapts and ...

Globally, about 35 million people are living with HIV, which constantly adapts and mutates creating challenges for researchers. Now, scientists are gaining a clearer idea of what a key protein in HIV ...

Scientists at the Electron Bio-Imaging Centre (eBIC) at Diamond Light Source, in the U.K., have harnessed a new technique, using cryo-electron tomography (cryoET) and subtomogram averaging (STA) to ...

Cambridge, MA, November 28, 2019 -- Dyno Therapeutics, a biotechnology company pioneering use of artificial intelligence in gene therapy, today announced a publication in the journal Science that ...

RIVERSIDE, Calif. -- Research led by a physicist at the University of California, Riverside, shows how viruses form protective shells, or capsids, around their genomes — a process that, while messy ...

Human immunodeficiency virus type 1 (HIV-1) targets important cells of our immune system, making infected individuals more vulnerable to diseases and infections. Once inside human cells, HIV ...

Most proteins fulfil their function as part of large protein complexes. Surprisingly, little is known about the pathways and regulation of protein assembly. Several viral coat proteins can ...

For most of his career at Gilead Sciences, medicinal chemist Winston Tse has lived and breathed one thing. While his peers at other companies hopped from project to project, Tse has spent the past ...