Although lenabasum failed to meet its efficacy endpoint in a trial of patients with diffuse cutaneous systemic sclerosis, a post-hoc analysis suggests an impact on forced vital capacity, according ...

Patients with diffuse systemic sclerosis (SSc), without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis.

Nonetheless, "the impact on skin met the prespecified endpoint, which is the first time that this has been achieved in a phase II study in diffuse cutaneous systemic sclerosis," the team concluded.

The classically defined diffuse subtype of juvenile systemic sclerosis demonstrates more globally severe disease and higher interstitial lung disease frequency, whereas the limited cutaneous ...

Better Arthroplasty Outcomes, Hope in Scleroderma, and Other Rheumatology Advances Bret S. Stetka, MD Disclosures January 03, 2018 0 ...

After undergoing tests and seeing specialists, the garden designer was diagnosed with diffuse cutaneous systemic sclerosis, a type of scleroderma, a rare autoimmune condition which causes the skin ...

Systemic sclerosis is a rare but serious autoimmune disease which causes hardening and swelling of the skin, as well as joint pain, digestive problems, lung disease, and sometimes problems with ...

Diffuse cutaneous scleroderma (also known as systemic sclerosis) is a debilitating chronic disease affecting predominantly women and leading to significant disability, including hand dysfunction ...

Systemic scleroderma, also called systemic sclerosis (SSc), is further divided into the limited cutaneous subset and the diffuse cutaneous subset, depending on the degree of skin involvement.

Patients who underwent autologous stem cell transplantation (ASCT) for diffuse cutaneous systemic sclerosis (dcSSc), also known as scleroderma, did no better than others receiving conventional ...

AMSTERDAM — For patients with diffuse cutaneous systemic sclerosis, an autoimmune disease for which there are few treatment options, lenabasum (JBT-101, Corbus Pharmaceuticals) shows potential ...

Systemic scleroderma is characterized as either being limited or diffuse. People with limited systemic scleroderma usually have a combination of symptoms, mostly but not entirely related to the skin.