Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death globally, with incidence continuing to rise in many regions. Despite advances in ...

Figure 1: KMAP visualisation of SELEX-seq data for the transcription factor MAFK. Each dot represents a k-mer. Clusters of k-mers at the center correspond to DNA motifs, while the surrounding dots ...

Powered by gene editing advances like CRISPR and base editing, cell and gene therapy (CGT) is delivering on the promise of genomic medicine. First-generation CAR T-cell therapies, for example, have ...

Scientists have unveiled two major CRISPR breakthroughs: a ThermoCas9 variant that can distinguish and cut tumor DNA while sparing healthy cells, and a retron-based editing system adapted from E. coli ...

Schematic of the CRISPR/Cas9 system and its nanotechnology delivery methods. The CRISPR/Cas9 system can be delivered in the forms of DNA, mRNA/sgRNA, or ribonucleoprotein (RNP). The gene editing tools ...

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins are core components of fast-evolving therapeutic gene editing tools. Scientists have used CRISPR ...

That is because scientists keen to achieve more precise control over an organism’s genetics are experimenting with a ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

Learn more Eli Lilly is locking down on its rapid expansion strategy with a second deal this week – joining forces with artificial intelligence (AI) biotech, Profluent, to develop recombinases for ...

J. Craig Venter, the scientist who led the private effort to sequence the first draft of the human genome, has died at age 79 in San Diego. His work accelerated genetic research, revealing links ...