When scientists opened the doors of a research facility and let carefully bred lab mice loose into a fenced field, they expected skittish, fragile animals to struggle. Instead, the mice rapidly shed ...

When laboratory mice step out of their plastic cages and into real soil, their behavior changes so dramatically that it forces a rethink of what stress, health and even “normal” really mean. The story ...

Conventional laboratory mice housed under specific pathogen-free (SPF) conditions are the standard model in biomedical research. However, in recent years, many rodent-based studies have been deemed ...

Researchers have created genome-wide, high-resolution genetic maps of 100 inbred mouse strains. Compared with wild-derived strains, most of today's classical lab strains have limited genetic diversity ...

Scientists stress out lab mice, a lot. Inducing chronic stress and anxiety in these furry critters is how scientists explore the bodily and cognitive effects of stress and discover anti-anxiety ...

Assembly of the mammalian gut microbiota during early life is known to shape key aspects of organismal development, including immunity, metabolism and behaviour. While house mice (Mus musculus) are ...

In the world of biomedical research, the humble lab mouse is a superstar—it’s easy enough to rear in large quantities, shares a considerable amount of core biological processes with humans, and is ...