Dear Dr. Roach: Many years ago, while I was battling breast cancer, a scan showed spots of concern in my midthoracic area. Upon further testing, it was determined that I have sarcoidosis. My ...

Pulmonary sarcoidosis is a condition that causes tiny groups of immune cells to clump in your lungs. These groups of cells form swollen, inflamed lumps called granulomas. Granulomas can make it hard ...

Objectives To characterise the aetiological spectrum of thoracic granulomatous diseases and identify diagnostic features that facilitate differentiation among causes. Design Retrospective multicentre ...

MicroCT of infected human lung tissue, along with histology and immunohistochemistry, was used to construct images of TB granulomas, airways and vasculature. For 70 years, clinicians thought they knew ...

Neutrophils induce anti-inflammatory -- or M2 -- macrophages deep in their granulocyte core. The dense globular structures of granulomas in animals, particularly in the lungs, have been studied.

See References Table 1 in the Supplementary Appendix, available with the full text of this article at NEJM.org, for additional references pertaining to this table. An adverse prognosis indicates a ...

Two new studies cast light on disease processes in tuberculosis (TB), identifying key genetic changes that cause damage in the lungs and a drug treatment that could speed up recovery. The findings are ...

Histoplasmosis is a fungal infection that can cause swelling, inflammation, and, sometimes, small semi-opaque or calcified nodules on the lungs. However, histoplasmosis does not always cause symptoms.

The immune response against tuberculosis (TB) infections develops at least twice as slowly as that triggered by other infectious diseases that affect the lungs. A study in non-human primates by ...

Kyoto, Japan -- When our bodies become infected, various immune responses are triggered, starting with a release of granulocytes, white blood cells containing special enzymes that make up about half ...