Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their ...

Scientists have developed a new imaging technique that uses a novel contrast mechanism in bioimaging to merge the strengths of two powerful microscopy methods, allowing researchers to see both the ...

The field of Brillouin microscopy and imaging was established approximately 20 years ago, thanks to the development of non-scanning high-resolution optical spectrometers. Since then, the field has ...

Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...

The resolution and contrast of microscope imaging is often affected by aberrations introduced by imperfect optical systems and inhomogeneous refractive structures in specimens. Adaptive optics (AO) ...

Nonlinear Raman microscopy techniques, such as coherent anti-Stokes Raman scattering and stimulated Raman scattering, are widely used to provide chemical and spatial information. A third nonlinear ...

Introduction to SNOM: The Scanning Near-field Optical Microscope (SNOM) stands as a pivotal analytical tool in nanotechnology, enabling the visualization of nanostructures with resolution beyond the ...

Definition: Scanning Tunneling Microscopy (STM) is a powerful nanoscale imaging technique capable of providing atomic-level resolution of surface structures. By utilizing the quantum mechanical ...

Chemists discover how key contrast agent works, paving a way to create new markers needed for correlative microscopy that can image the structure and signaling of cells at the same time. Two labs at ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

A completely new type of microscope can take 3D images of cells -- while working in a natural environment. The new technology is significantly faster and better than before and will give researchers ...

First author Karl D. Briegel (l.) with Prof Dominik B. Bucher and their new microscope. The resolution of the new MRI microscope reaches ten-millionths of a meter - that is so fine that even the ...