The Week 6 NFL slate is headlined by a fascinating Sunday night matchup between the Lions and a Chiefs team looking to avoid a 2-4 start.

The Carolina Panthers failed their first big test of the Andy Dalton era this past Sunday, getting blown out on the road by the Chicago Bears by 26 points. As you might imagine, there's not a whole lot of confidence in them to get the job done this coming ...

Week 10 brought plenty of stunners, including the Miami Dolphins routing the rival Buffalo Bills and Los Angeles Chargers blanking the Pittsburgh Steelers in prime time. Now we've got another slate full of intriguing action in Week 11.

The Arizona Cardinals face the San Francisco 49ers in Week 11. It is their second matchup of the year. After a Week 3 loss in Santa Clara, the Cardinals now host the game at State Farm Stadium. The Cardinals are 3-6 and have lost six of their last seven games. The 49ers are 6-4.

After a 2-0 start to the season — when NFL media were starting to talk Super Bowl — the Green Bay Packers have been a major disappointment to their fans. And to bettors. The Packers have gone from 2-0 to 6-3-1.

After surviving a heavyweight fight with the Packers on Monday night, the Eagles return to Lincoln Financial Field for Round 2 of dealing with an NFC North heavyweight. Philadelphia is one of only six NFL teams with two losses, joining Denver (8-2), Indianapolis (8-2), New England (8-2), the L.A. Rams (7-2), and Seattle (7-2) as they enter Week 11.

The Buccaneers are clear underdogs in their Week 11 trip to Western New York, and most NFL analysts are siding with the home team in a battle of 6-3 squads

The Steelers are 5.5-point favorites in the latest Steelers vs. Bengals odds at SportsLine, and the over/under for total points scored is 48.5. Pittsburgh is a -245 money line favorite (risk $245 to win $100),