Penicillinase is an enzyme that acts on the β-lactam ring of penicillin to convert penicillin into penicillic acid, which has no antibacterial activity. A variety of penicillin-resistant bacteria can ...

Penicillinase production in strains of bacillus in which such production is constitutive, as well as in strains in which it is inducible, was found to be a function of the type of penicillin to which ...

WHILE studying the kinetics of penicillinase inactivation of various penicillins, it became evident that a penicillinase-susceptible penicillin, such as benzyl-penicillin, behaved differently from ...

WITH the long-acting depot penicillins in general use today, prolonged blood levels also prolong the sensitivity reactions when they occur. The use of ACTH and cortisone as anti-inflammatory agents to ...

WHEN the results of a gram stain or culture of material in a serious case of staphylococcal infection become known, and before the susceptibility of the organism has been determined, the physician is ...

The penicillin family represents one of the most valuable groups of antibiotics in practically every area of modern healthcare. They are bactericidal, well distributed, and highly effective against ...