A recent study uncovers how drug-resistant cancer cells induce changes in the tumor microenvironment. This phenomenon promotes cancer recurrence and explains why initially effective targeted therapies ...

A research team has discovered a crucial mechanism that underlies chemotherapy resistance and metastasis in small cell lung cancer (SCLC). Their study shows that the silencing of the RASA4 gene ...

Ovarian cancer treatment faces challenges with high relapse and drug resistance rates, despite initial chemotherapy effectiveness. Cytokines like IL-6 and IL-11 are associated with complex tumor ...

Antimicrobial resistance (AMR) is diminishing the effectiveness of existing antibiotics and intensifying the need for discovery pipelines that are both ...

Panelists discuss how overcoming resistance to EGFR TKIs requires next-generation inhibitors and more individualized treatment strategies. Panelists discuss how resistance to EGFR tyrosine kinase ...

HER2 and ABCC1 are identified as significant transcriptomic predictors of overall survival in patients treated with T-DXd. A large-scale analysis reveals novel predictors of survival and resistance ...

Metagenomic libraries have been prepared to screen for the presence of antibiotic resistance genes in tiny environmental samples. Scientists from the University of Illinois Urbana-Champaign College of ...

Last fall, more than 100 people in 14 states got sick after eating at McDonald’s. The Centers for Disease Control and Prevention traced the outbreak to raw onions on the quarter-pounder hamburger, ...

Imagine that two women have breast cancer with the same subtype: hormone receptor positive (HR+) and human epidermal growth factor receptor 2 negative (HER2-). They’re the same age, weight, and height ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...