Single-molecule fluorescence spectroscopy has emerged as a transformative technique in the study of biomolecular structure and dynamics. By utilising individual fluorescent probes, this approach ...

Single-molecule force spectroscopy (SMFS) has emerged as a powerful approach to probe the mechanics, kinetics and energetics of individual biomolecules as they undergo folding, binding and chemical ...

A collaborative research team from Kanazawa University and Kyoto University reports the successful visualization of how densely assembled macrocyclic host molecules cooperatively capture guest ...

What is Fluorescence Correlation Spectroscopy (FCS)? Fluorescence correlation spectroscopy (FCS) is a powerful analytical technique that enables the study of dynamic processes and interactions at the ...

In a recent article published in Nature Nanotechnology, researchers introduced an approach in single-molecule spectroscopy, significantly improving the ability to probe quantum transitions in ...

This fundamental limitation severely constrains the detection sensitivity. Developing single-molecule Raman spectroscopy (SM-RS) to achieve Raman signal intensity comparable to fluorescence signals ...

Pumpkinseed founders Jennifer Dionne, Jack Hu, and Nhat Vu discuss their nanophotonic chip platform that promises label-free, ...

Figure 1. (a) Schematic diagram of the optical trapping-enhanced SERS optofluidic detection system; (b) effect of the single-beam optical trap module switch state on AgNPs aggregation; (c1) and (c2) ...