Researchers have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport neurotransmitters in the brain. The study could inform ...
In A, researchers used a fluorescent protein (synaptopHluorin) to visualize synaptic vesicle movement. Some vesicles stay open briefly before retrieval (kiss-and-run). Others stay open longer but also ...
Northwestern University researchers have reported that levetiracetam, a long-established anti-epileptic medicine, prevented ...
Behavioral assays linked these molecular disturbances to functional outcomes. Exposed fish displayed increased locomotor activity, heightened anxiety-like behavior, and altered learning performance, ...
How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...
α-synuclein (α-syn) is a small presynaptic protein linked to the pathogenesis of Parkinson’s disease (PD) and related disorders, collectively called synucleinopathies. Phosphorylation of α-syn at ...
How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...
While physicians and scientists have long known that Alzheimer's disease involves the buildup of toxic protein fragments in ...
Max Delbrück Center for Molecular Medicine in the Helmholtz Association Researchers led by Uljana Kravčenko and her colleagues in the lab of Professor Misha Kudryashev, Group Leader of the In Situ ...
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