Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in ...

Unlike nuclear DNA, mitochondrial DNA (mtDNA) is circular in nature and organized as mitochondrial nucleoids comprised of DNA-protein complexes that are distributed in the matrix. It is also inherited ...

There are a total of 5 multi-subunit complexes in the inner membrane of the mitochondria, all of which are involved in the process of oxidative phosphorylation that precedes ATP production. Of these, ...

The findings may have important implications for diseases linked to mitochondrial dysfunction. A newly identified form of DNA damage inside mitochondria, the small structures that supply energy to our ...

Back in the 19 th century, as the US grappled with the aftermath of the Civil War, Jesse James, leader of a notorious gang of outlaws, rose to prominence. He robbed banks and trains for over a decade ...

Mitochondrial remodeling during the peri-implantation stage is the hallmark event essential for normal embryogenesis. Among the changes, enhanced oxidative phosphorylation is critical for supporting ...

Relative influence of factors determining a woman’s preference for treatment options in ovarian cancer. A randomized phase II trial of bevacizumab (BV) plus oral everolimus (EV) versus bevacizumab ...

Provide each team with a copy of "The Hunt for mtDNA" student handout. Explain to students what mtDNA is, how it differs from nuclear DNA, and how it is inherited (see Activity Answer for more ...

You are a forensic scientist recruited to help solve a long-standing "missing persons" case. Mitochondrial DNA, or mtDNA for short, is the key to your success. Take careful notes as your teacher ...