Immunotherapy, Chemotherapy, or Both: Options for First-Line Therapy for Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma ...

To advance the call to action to optimize dosage of anticancer agents, FDA and ASCO cosponsored two multistakeholder workshops, Getting the Dose Right: Optimizing Dose Selection Strategies in Oncology ...

Upper tract urothelial carcinoma (UTUC) is one of the common urothelial cancers. Although large cohorts have illustrated spectrum of germline mutations, landscape of somatic alterations has not been ...

Early-phase clinical trials (EPCTs) have been increasingly adopted as the pivotal trial to support US Food and Drug Administration (FDA) approval of novel anticancer drugs. Among EPCT designs, ...

Author's Disclosures of Potential Conflicts of Interest No Versus Know: Patient Empowerment Through Shared Decision Making ...

We aimed to assess whether lung cancer (LC) screening with low-dose computed tomography (LDCT) is cost effective in a high-risk population (current or former smokers—who stopped smoking within <15 ...

Immunotherapy-based combinations have shown promising survival benefits in patients with hepatocellular carcinoma (HCC) included in clinical trials. However, real-world data are needed to assess the ...

In this JCO Article Insights episode, Michael Hughes summarizes “ International Myeloma Society and International Myeloma Working Group Consensus Recommendations on the Definition of High-Risk ...

In the article that accompanies this editorial, Yin et al 12 present the early phase development and validation of a fragmentomics-based biomarker for the earlier detection of pancreatic cancer. While ...

In this JCO Precision Oncology Article Insights episode, Natalie DelRocco summarizes "Prognostic Value of the G2 Expression Signature and MYC Overexpression in Childhood High-Grade Osteosarcoma" by ...

Systematic mediastinal lymph node dissection (LND) or sampling is currently recommended for patients with early-stage non–small cell lung cancer. We aimed to investigate whether no mediastinal LND was ...

PURPOSEThe surveillance protocol for early-stage non–small cell lung cancer (NSCLC) is not contingent upon individualized risk factors for recurrence. This study aimed to use comprehensive data from ...