Background Aortic valve calcification (AVC) is a disease process driven by inflammation and lipid infiltration, serving as a ...

Background The Fontan procedure is associated with long-term cardiac and non-cardiac complications and early mortality. Recent data suggest that some fibrosis scores may offer prognostic insight for ...

Correspondence to Dr Kathleen W. Zhang, Cardiovascular Division, Department of Internal Medicine, Washington University in St Louis School of Medicine, St Louis, Missouri 63110, USA; ...

Background Sinoatrial node dysfunction and atrial fibrillation (AF) often coexist, and each potentially initiates or perpetuates the other. Consequently, genetic risk factors for AF may be associated ...

Background Socioeconomic disparities are associated with sudden cardiac arrest (SCA) in older populations, but evidence in young adults is limited. We investigated the association between income ...

Objective First-degree atrioventricular block is frequently encountered in clinical practice and is generally considered a benign process. However, there is emerging evidence that prolonged PR ...

2 Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, University of Lisbon, Lisboa, Portugal 3 Cardiology Department, CCUL, CAML, Faculty of Medicine, Lisbon, Portugal 4 ...

Correspondence to Dr Pierre-Antoine Dugué, Cancer Epidemiology and Intelligence Division, Cancer Council Victoria, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global ...

Familial hypercholesterolaemia (FH) is a common autosomal-dominant disorder in most European countries. Patients with FH are characterised by a raised level of low-density lipoprotein cholesterol and ...

Objective Although the factors associated with short-term survival from out-of-hospital cardiac arrest (OHCA) are well established, relatively little is known about the factors that influence ...

Objective In 2014, the European Society of Cardiology (ESC) recommended the use of a novel risk prediction model (HCM Risk-SCD) to guide use of implantable cardioverter defibrillators (ICD) for the ...

Objective More knowledge about the development of sudden cardiac death (SCD) in the general population is needed to develop meaningful predictors of SCD. Our aim with this study was to estimate the ...