From a jaw-dropping wolfdog litter to a corgi cross, these Great Dane mixes took over the internet for all the right reasons.

Lambeau the Great Dane is "a little menace" when it comes to socks, and he will find a way to steal them no matter where they ...

Hilda is a 4-year-old Great Dane who lost her eyesight, but that hasn't stopping her from looking for a loving family to call ...

The oldest player to ever appear in an NFL game was George Blanda, who played quarterback and kicker in pro football for 26 ...

The Great Dane, also known as the Apollo of dogs, is a giant breed. The breed is thought to have been around for more than 400 years. Great Danes descend from mastiff-like dogs that were bred by ...

Our Pet of the Week is Moe, a 10-year-old Great Dane/Labrador mix, and he is just one of the many animals available at the ...

A Great Dane who got stuck in a culvert in Colorado Springs is now back safe with his family, thanks to the quick actions ...

JACKSONVILLE, Fla. — Candlelight filled the front of Animal Care and Protective Services in Riverside Monday night as the agency held a vigil for Miracle. The three-year-old Great Dane passed away ...

Rebecca Gayheart—who shares two kids with estranged husband Eric Dane—packed on the PDA with Peter Morton on Dec. 3, weeks ...

The 53-year-old actor, who revealed his diagnosis in April, admitted to Us Weekly on Wednesday that his abilities are "fairly limited." ...

The oldest player to ever appear in an NFL game was George Blanda, who played quarterback and kicker in pro football for 26 ...

Months after Eric Dane shared his ALS diagnosis, the Grey's Anatomy star detailed why he decided to be an advocate for the disease with the help of his star power.