San Jose Earthquakes (8-11-8, 10th in the Western Conference) vs. Houston Dynamo (7-11-8, 12th in the Western Conference) ...

Portland Timbers (10-9-7, seventh in the Western Conference) vs. San Diego FC (16-7-4, first in the Western Conference) ...

Orlando City SC (13-6-8, third in the Eastern Conference) vs. Nashville SC (14-8-5, second in the Western Conference) ...

New England Revolution (7-12-7, 10th in the Eastern Conference) vs. Columbus Crew (12-5-9, fourth in the Eastern Conference) ...

Inter Miami CF (13-5-6, fourth in the Eastern Conference) vs. DC United (4-15-8, 13th in the Eastern Conference) ...