Differentiation of induced pluripotent stem cells (iPSCs) toward neuronal lineages has enabled diverse cellular models of human neurodevelopment and related disorders. Here, we jointly profiled ...
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Thanks to the plummeting costs of continuously evolving omics analytical platforms, ...
Vein graft failure following cardiovascular bypass surgery results in significant patient morbidity and cost to the healthcare system. Vein graft injury can occur during autogenous vein harvest and ...
Epigenetic age estimators (clocks) are predictive of human mortality risk. However, it is not yet known whether the epigenetic age of atherosclerotic plaques is predictive for the risk of ...
The adipose tissue is a central hub of metabolic and endocrine regulation with a major impact on aging. We identify the conserved miRNA-processing enzyme Dicer-1 (Dcr-1) as a crucial regulator of ...
1 Department of Laboratory, Yangbi Yi Autonomous County People’s Hospital, Dali, China. 2 Department of Obstetrics and Gynecology, Yangbi Yi Autonomous County People’s Hospital, Dali, China. 3 ...
Fluid shear stress mediates vascular homeostasis by regulating gene expression in endothelial cells (ECs). Using single-cell RNA sequencing, this study provides a comprehensive perspective of ...
Background: Esophageal carcinoma (ESCA) is one of the most prevalent malignant tumors in the world. The prognosis of patients has significantly improved with the development of surgery, targeted ...
Differentiation of B cells into antibody-secreting cells (ASCs) is a key process to generate protective humoral immunity. A detailed understanding of the cues controlling ASC differentiation is ...
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