New research shows epigenetic silencing may limit durability of AAV gene therapy in haemophilia by reducing long term transgene expression in liver cells.

All the main Adobe software programs and what to use them for.

While previous embedding models were largely restricted to text, this new model natively integrates text, images, video, audio, and documents into a single numerical space — reducing latency by as muc ...

Cas9, Transcription Activator-Like Effector Nucleases (TALENs), and Zinc-Finger nucleases (ZFNs) have demonstrated great utility, primarily for genetic knock-out applications, none have been adopted ...

Naked mRNA administration in the testes rescues sperm function, demonstrating a potential therapeutic approach for genetic male infertility.

Here’s a quick library to write your GPU-based operators and execute them in your Nvidia, AMD, Intel or whatever, along with my new VisualDML tool to design your operators visually. This is a follow ...

In previous work, researchers from CEINGE (Naples, Italy) and collaborating institutions developed an alternative gene therapy strategy based on the expression of a secreted fusion protein, including ...

Multichain biotherapeutics continue to be a promising therapeutic modality. “These therapeutic recombinant proteins are typically assembled from at least three distinct polypeptide chains,” says ...

All aspects of upstream bioprocessing are under pressure to increase expression titers and improve product quality (PQ). To date, major advancements in the glutamine synthetase (GS) system for Chinese ...

Plasma cells provide protective antibodies following an infection or vaccination. A network of intrinsic and extrinsic factors fine-tunes the generation of a heterogenous plasma cell pool with varying ...