The finding that spermine molecules in cells bind to iron to prevent it unleashing ferroptosis, a type of cell death, opens up strategies for treating tissue damage and cancer.
PARP inhibitors kill cancer cells by trapping poly(ADP-ribose) polymerase 1 (PARP1) on DNA. A study now shows that cancer cells use a specialized form of autophagy to extract and degrade trapped PARP1 ...
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