Cleveland Browns rookie running back Quinshon Judkins was carted off the field shortly before halftime of the team's eventual 23-20 loss to the Buffalo Bills after suffering a serious right leg injury. Kevin Stefanski told reporters that Judkins fractured his fibula and dislocated his ankle, per ESPN. His first NFL season is over.

The loss wasn't all on Sanders, but he did have two chances to lead the Browns to a game-tying or go-ahead score late in the fourth quarter.

Mary Kay Cabot, Ashley Bastock, Dan Labbe will go live Sunday night and get into what they saw on a live edition of the Orange and Brown Talk podcast. They’ll talk about what they saw from Sanders and where things stand as the Browns head into the final two weeks of the season.

The Buffalo Bills (11-4) got a step closer to clinching a playoff spot with a 23-20 win over the Cleveland Browns (3-12) on Sunday. Running back James Cook led the Bills with 117 yards rushing and two touchdowns. He eclipsed the 100-yard rushing mark for the ninth time this season.

Browns leading rusher Quinshon Judkins was carted off during the team's NFL Week 16 loss to the Buffalo Bills.

CLEVELAND, Ohio — Browns rookie running back Quinshon Judkins should be back on the practice field in about 4-5 months after undergoing surgery to repair a dislocated right ankle and fractured fibula, a league source told cleveland.com.

Watch the Tennessee Titans top plays in Week 16 from the team's 26-9 win over the Kansas City Chiefs. Watch the Minnesota Vikings' top plays vs. the New York Giants from Week 16 of the 2025 NFL season. The Cincinnati Bengals' top plays vs. the Miami Dolphins during Week 16 of the 2025 NFL season.

Josh Allen and the Buffalo Bills held off Shedeur Sanders and the Cleveland Browns, earning a 23–20 road victory on Sunday.