Michele Singer Reiner’s mother, Nicole Silberkleit (née Bernheim), was a Holocaust survivor whose parents and brother were killed at Auschwitz. Nicole recorded her Holocaust testimony in November 1994.

Reiner and his son Nick explored their troubled relationship in a 2015 semi-autobiographical film Being Charlie, which chronicled Nick’s struggles with addiction, cycles of rehab, and bouts of homelessness in between. Rob Reiner directed the movie, and Nick Reiner co-wrote it.

An air of wisdom and authority beyond her years made Michele well suited to deal with photo subjects from the corporate world like real estate tycoon Samuel Jayson LeFrak and then-future president Donald Trump, whose portrait she shot for the cover of his 1987 book, The Art of the Deal.

Mr. Reiner’s falling for his wife of 36 years inspired the director to rework the ending of “When Harry Met Sally …” The couple would collaborate on movies and political causes.

In mid-December 2025, a Facebook post claimed to quote actress and singer Barbra Streisand reacting to the slaying of famed director Rob Reiner and his wife, Michele Reiner. Per the post, Streisand allegedly mourned their deaths while saying it was "no accident."

Rob and Michele Reiner's final hours were spent with their son, Nick, who now is accused of killing them. Inside the final, chilling hours.

Nick Reiner hizo su primera aparición en la corte en Los Ángeles por dos cargos de asesinato en primer grado por el homicidio de sus padres, el actor y director Rob Reiner y su esposa Michele Singer Reiner,

Rob Reiner and Michele Singer Reiner's children, Jake and Romy Reiner, remembered their parents in their first statement since the couple's deaths: 'Words cannot even begin to describe the unimaginable pain.