Van Patten tells PEOPLE she remembers worrying, "What would [Knox] think of me, this random actress portraying her in a very traumatic time of her life?"

"The Twisted Tale of Amanda Knox" is a dramatization of the real-life events surrounding Seattle native Amanda Knox. Here's how to watch the series.

"The Twisted Tale of Amanda Knox" premieres on Hulu on Wednesday, Aug. 20 with its first two episodes and will air weekly until the finale on Oct. 1.